Scientific program
Tuesday, May 20, 2025
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Time
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Event
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(+)
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15:00 - 18:00
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Registration
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16:00 - 18:00
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Proteocure MC and CG meeting (open only to members of ProteoCure's Management Committee and Core Group)
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18:20 - 18:30
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Opening remarks
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18:30 - 19:30
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Opening lecture -THE EMBO LECTURE
Nucleo-cytosolic translocation of the 26S proteasome as a novel regulatory stress coping mechanism and drug development platform - Aaron Ciechanover (Technion Israel Institute of Technology, IL)
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19:30 - 21:00
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Welcome Reception
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Wednesday, May 21, 2025
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Time
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Event
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(+)
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09:00 - 10:15
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SESSION 1: Quality Control of Protein Biogenesis
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09:00 - 09:30
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A Cryptic Ubiquitin Ligase Activity Suppresses Deterioration Accompanying Alzheimer's Disease. - Michael Glickman (Technion Israel Institute of Technology, IL)
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09:30 - 10:15
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Short talks
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10:15 - 10:45
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Coffee break
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10:45 - 12:30
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SESSION 2: Ubiquitin & Ubiquitin like modifiers
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10:45 - 11:15
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Deciphering the ubiquitin code through biotin-based strategies - Rosa Barrio (CIC bioGUNE, ES)
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11:15 - 12:00
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Short talks
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12:00 - 12:30
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Flash Talks
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12:30 - 13:30
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Lunch
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13:30 - 16:30
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SESSION 3: Proteolytic Machinery-Proteasome
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13:30 - 14:00
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The role of proteasome heterogeneity in the proteostatic network: lessons from rare proteasomopathies. - Elke Krüger (University of Greifswald, DE)
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14:00 - 14:30
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Short Talks
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14:30 - 16:30
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Poster session
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16:30 - 22:30
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Conference Excursion & Dinner - Visit in Knosos & Dinner in local Winery
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Thursday, May 22, 2025
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Time
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Event
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(+)
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09:00 - 10:15
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SESSION 4: Autophagy/Mitophagy/Lysosomal proteases I
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09:00 - 09:30
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Keeping mitochondria in shape: a matter of life and death - Luca Scorrano (University of Padova, IT)
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09:30 - 10:15
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Short talks
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10:15 - 10:45
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Coffee break
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10:45 - 12:00
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SESSION 5: Autophagy/Mitophagy/Lysosomal proteases II
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10:45 - 11:15
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Cathepsin S – friend or foe in cancer - Christopher Scott (Queen’s University, Belfast, IE)
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11:15 - 12:00
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Short Talks
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12:00 - 12:30
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ELSEVIER PRESENTATION (online)
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12:30 - 13:30
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Lunch
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13:30 - 18:00
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SESSION 6: From Bench to Bedside
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13:30 - 14:00
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Translating translation in neurodegeneration - Giovanna Mallucci (Altos Labs Cambridge Institute of Science, GB)
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14:00 - 14:45
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Short Talks
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14:45 - 15:15
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Pharmacological exploitation of neurotrophins and their receptors against neurodegeneration: from the bench to the clinic - Nektarios Tavernarakis (FORTH-IMBB, GR)
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15:15 - 16:00
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Coffee break
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16:00 - 16:30
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Pharmacological exploitation of neurotrophins and their receptors against neurodegeneration: from the bench to the clinic - Ioannis Charalampopoulos (IMBB-University of Crete, GR)
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16:30 - 17:00
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Genetic architecture of Parkinson disease on the island of Crete - Cleanthe Spanaki (University of Crete, GR)
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17:00 - 18:00
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Short Talks
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Friday, May 23, 2025
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Time
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Event
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(+)
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09:00 - 10:15
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SESSION 7: Targeting proteolysis -Drug discovery
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09:00 - 09:30
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ECM Proteolytic Damage Imprints Perpetuate Chronic Inflammation - Irit Sagi (Weizmann Institute of Science, IL)
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09:30 - 10:00
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Short talks
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10:15 - 10:45
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Coffee break
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10:45 - 11:00
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Award ceremony for poster and short talk prizes
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11:00 - 11:30
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Closing remarks
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